Preparation and characterization of a novel host-guest complex based on folate-modified β-cyclodextrin and artesunate.


The purpose of this study was to develop a novel folate-modified host-guest complex to enhance antitumor activity of the artesunate and improve the solubility and stability by encapsulated in β-cyclodextrin and linked with folate. In this work, we designed and prepared the inclusion complex of adamantanamine conjugated artesunate (AD-ATS) with folic acid… (More)
DOI: 10.1016/j.msec.2017.12.009


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