Preparation and characterization of a new gellan gum and sulphated hyaluronic acid hydrogel designed for epidural scar prevention.

@article{Cencetti2011PreparationAC,
  title={Preparation and characterization of a new gellan gum and sulphated hyaluronic acid hydrogel designed for epidural scar prevention.},
  author={Claudia Cencetti and Davide Bellini and Cristina Longinotti and Andrea Martinelli and Pietro Matricardi},
  journal={Journal of materials science. Materials in medicine},
  year={2011},
  volume={22 2},
  pages={263-71}
}
Postsurgical adhesions are a common problem in clinical practice, causing nerve compression, pain and discomfort. A new hydrogel based on gellan gum and sulphated hyaluronic acid was synthesized, with the aim to create an effective barrier for epidural scar formation. Physico-chemical properties of the gel were analyzed, and preliminary biocompatibility data (i.e. cytotoxicity) have been collected in view of its potential clinical use. The characterization of the new material demonstrated that… CONTINUE READING