Preparation and antidiabetic activity of new substituted 3,5-diarylpyrazolesulfonylurea derivatives. II: Structure-activity relationship.

@article{Soliman1987PreparationAA,
  title={Preparation and antidiabetic activity of new substituted 3,5-diarylpyrazolesulfonylurea derivatives. II: Structure-activity relationship.},
  author={Raafat Soliman and Hassan Faid-Allah and S K el-Sadany},
  journal={Journal of pharmaceutical sciences},
  year={1987},
  volume={76 8},
  pages={626-32}
}
Four series of substituted p-(3,5-diaryl-2-pyrazoline-1) benzenesulfonylurea and thiourea derivatives, along with their corresponding substituted p-(3,5-diarylpyrazole-1) benzenesulfonylurea and thiourea derivatives, were prepared for evaluation as hypoglycemic agents. Preliminary biological testing revealed that the new compounds possess potent… CONTINUE READING