Design, development and in vitro-in vivo study of a colon-specific fast disintegrating tablet.
- Sanjay J Kshirsagar, Mangesh R Bhalekar, Rajesh R Umap
- Pharmaceutical development and technology
- 2011
1 Excerpt
Preparation and Characterization of Nicotine / Ca-alginate Composite Microcapsules for the Enteric Controlled Drug Release
- Published 2013
Abstract
The aim of the present study was to develop drug-loaded microcapsules to increase drug bioavailability at target site especially for colon-targeted oral delivery. Nicotine was selected as a model lipophilic drug. Additives such as gelatin, glycerin and PEG 6000 were added into Ca-alginate composite to prepare microcapsules by using a modification of the… (More)