Preparation and Characterization of Polycaprolactone Nanofibers for the Controlled Release of Chlorogenic Acid

@article{Ranjith2017PreparationAC,
  title={Preparation and Characterization of Polycaprolactone Nanofibers for the Controlled Release of Chlorogenic Acid},
  author={R. Ranjith},
  journal={International Journal for Research in Applied Science and Engineering Technology},
  year={2017},
  pages={234-238}
}
  • R. Ranjith
  • Published 2017
  • Chemistry
  • International Journal for Research in Applied Science and Engineering Technology
Electrospun nanofibers have gathered more consideration in worldwide to deliver the bioactive agents in a sustained manner for biomedical applications. In this study, chlorogenic acid loaded polycaprolactone nanofibers were fabricated by electrospinning process and the average fiber diameters were analyzed using scanning electron microscopy analysis. Further, Fourier transform infrared spectroscopy results confirmed that the encapsulated chlorogenic acid was not modified chemically during the… Expand

Figures from this paper

References

SHOWING 1-10 OF 25 REFERENCES
Electrospun Polycaprolactone Nanofibers for Sustained Release of Naringin
Electrospun nanofibers have enormous potential to deliver bioactive molecules in a sustained manner for various drug delivery applications. In this study, naringin loaded polycaprolactone nanofibersExpand
Polycaprolactone nanofibers for the controlled release of tetracycline hydrochloride
Abstract Controlled delivery of drugs is one of the widely explored areas in biomedicine and healthcare. Biocompatible nanofibers are explored as potential drug delivery vehicles in recent years inExpand
Electrospun nanofiber-based drug delivery systems
TLDR
There are more opportunities to be exploited from the electrospinning process and the corresponding drug-loaded nanofiber preparation from pharmaceutical and biode-gradable polymers and different types of DDS. Expand
Biodegradable electrospun fibers for drug delivery.
  • J. Zeng, Xiaoyi Xu, +4 authors X. Jing
  • Chemistry, Medicine
  • Journal of controlled release : official journal of the Controlled Release Society
  • 2003
TLDR
It was shown that the drugs were capsulated inside of the fibers and the drug release in the presence of proteinase K followed nearly zero-order kinetics due to the degradation of the PLLA fibers. Expand
Electrospun curcumin loaded poly(ε-caprolactone)/gum tragacanth nanofibers for biomedical application.
TLDR
The fabricated PCL/GT/Cur-3% with suitable mechanical properties, excellent biological characteristics, and maintaining their original structure in degradation media may have potential application as a wound dressing patch for healing slow rate wounds. Expand
Structure and process relationship of electrospun bioabsorbable nanofiber membranes
Abstract An electrospinning method was used to fabricate bioabsorbable amorphous poly( d , l -lactic acid) (PDLA) and semi-crystalline poly( l -lactic acid) (PLLA) nanofiber non-woven membranes forExpand
Controlled green tea polyphenols release from electrospun PCL/MWCNTs composite nanofibers.
TLDR
The results exhibited that the GTP-loaded composite nanofibers possessed a significant inhibition effect to tumor cells, therefore, GTP, as a multifunctional drug, encapsulated into polymer composite nan ofibers, must have broad application prospects in cancer therapy. Expand
Camptothecin loaded poly(ε-caprolactone)nanofibers via one-step electrospinning and their cytotoxicity impact
Abstract The present study for the first time demonstrated the successful fabrication of camptothecin (CPT) loaded poly(e-caprolactone) (PCL) nanofibrous mats through one-step sol–gel electrospinningExpand
Chlorogenic acid loaded chitosan nanoparticles with sustained release property, retained antioxidant activity and enhanced bioavailability
Abstract In this study, chlorogenic acid (CGA), a phenolic compound widely distributed in fruits and vegetables, was encapsulated into chitosan nanoparticles by ionic gelation method. The particlesExpand
PHBV/PCL Microparticles for Controlled Release of Resveratrol: Physicochemical Characterization, Antioxidant Potential, and Effect on Hemolysis of Human Erythrocytes
TLDR
The hypochlorous-acid-scavenging activity and 2,2-azinobis(3-ethylbenzothiazoline-6-sulfonic acid) radical cation discoloration assay confirmed that the antioxidant activity of PHBV/PCL microparticles was kept, but was dependent on the microparticle morphology and dissolution profile. Expand
...
1
2
3
...