Preparation and Biopharmaceutical Evaluation of Novel Polymeric Nanoparticles Containing Etoposide for Targeting Cancer Cells
@article{Thiyagarajan2019PreparationAB, title={Preparation and Biopharmaceutical Evaluation of Novel Polymeric Nanoparticles Containing Etoposide for Targeting Cancer Cells}, author={A. Thiyagarajan and Shanmugam Saravanabhavan and V. Thangarasu}, journal={Turkish Journal of Pharmaceutical Sciences}, year={2019}, volume={16}, pages={132 - 140} }
Objectives: Polymeric nanoparticles are a promising novel drug delivery system and have advantages in cancer therapy. Etoposide is an anticancer agent that is used in the treatment of a variety of malignancies. The aim of the present study was to prepare and evaluate novel polymeric nanoparticles containing etoposide. Materials and Methods: A 32 full factorial design was used to study the effect of Eudragit EPO and Pluronic F-68 on the characterization of nanoparticle suspensions. The polymeric… CONTINUE READING
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