Preparation, characterization and targeting of micronized 10-hydroxycamptothecin-loaded folate-conjugated human serum albumin nanoparticles to cancer cells

@inproceedings{Li2011PreparationCA,
  title={Preparation, characterization and targeting of micronized 10-hydroxycamptothecin-loaded folate-conjugated human serum albumin nanoparticles to cancer cells},
  author={Qingyong Li and Chen Liu and Xiuhua Zhao and Yuangang Zu and Ying Wang and Baoyou Zhang and Dongmei Zhao and Qi Zhao and Lin Su and Yang Gao and Baihe Sun},
  booktitle={International journal of nanomedicine},
  year={2011}
}
BACKGROUND The purpose of this study was to develop a method for targeted delivery of 10-hydroxycamptothecin (HCPT)-loaded nanoparticles (NPs) to cancer cells. METHODS We first used a supercritical antisolvent process to prepare micronized HCPT (nHCPT), and then folate-conjugated human serum albumin (HSA) nHCPT-loaded NPs (FA-HSA-nHCPT-NPs) were prepared… CONTINUE READING