Preparation, characterization and protein loading of hexanoyl-modified chitosan nanoparticles.

@article{Desai2006PreparationCA,
  title={Preparation, characterization and protein loading of hexanoyl-modified chitosan nanoparticles.},
  author={Kashappa Goud H. Desai and Hyun Jin Park},
  journal={Drug delivery},
  year={2006},
  volume={13 5},
  pages={375-81}
}
Hexanoyl chitosan was synthesized through a coupling reaction between chitosan and hexanoic anhydride. Proton nuclear magnetic resonance (1HNMR) and fourier-transform infrared (FTIR) spectroscopy studies showed the formation of hexanoyl chitosan. The nanoparticles of hexanoyl chitosan were prepared through ionotropic gelation with tripolyphosphate (TPP) followed by sonication. The hexanoyl chitosan-TPP nanoparticles exhibited uniform spherical shape with smooth surface as observed by atomic… CONTINUE READING