Preparation, characterization and evaluation of breviscapine lipid emulsions coated with monooleate-PEG-COOH.

Abstract

Series of monooleate-modified PEG with active carboxylic terminus on the other end (MO-PEG-COOH) were used to modify the lipid emulsions surface to prepare a sterically stabilized lipid emulsions for carrying Traditional Chinese Medicine - breviscapine. Based on the research of relationship between polymer structure and prolonged circulation activity, we… (More)
DOI: 10.1016/j.ijpharm.2011.10.008

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