Preparation, biological activity and endogenous occurrence of N6-benzyladenosines.

  title={Preparation, biological activity and endogenous occurrence of N6-benzyladenosines.},
  author={Karel Dole{\vz}al and I. A. Popa and Eva Hauserov{\'a} and Luk{\'a}{\vs} Sp{\'i}chal and Kuheli Chakrabarty and Ondřej Nov{\'a}k and Vladim{\'i}r Kry{\vs}tof and Jiř{\'i} Voller and Jan Holub and Miroslav Strnad},
  journal={Bioorganic & medicinal chemistry},
  volume={15 11},
Cytokinin activity of forty-eight 6-benzyladenosine derivatives at both the receptor and cellular levels as well as their anticancer properties were compared in various in vitro assays. The compounds were prepared by the condensation of 6-chloropurine riboside with corresponding substituted benzylamines and characterized by standard collection of physico-chemical methods. The majority of synthesized derivatives exhibited high activity in all three of the cytokinin bioassays used (tobacco callus… CONTINUE READING

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