Preoperative vs postoperative initiation of low-molecular-weight heparin prophylaxis against venous thromboembolism in patients undergoing elective hip replacement.

@article{Hull1999PreoperativeVP,
  title={Preoperative vs postoperative initiation of low-molecular-weight heparin prophylaxis against venous thromboembolism in patients undergoing elective hip replacement.},
  author={Russell Douglas Hull and Rollin Frederick Brant and Graham Frederick Pineo and Paul D. Stein and Gary E. Raskob and Karen Aileen Valentine},
  journal={Archives of internal medicine},
  year={1999},
  volume={159 2},
  pages={137-41}
}
BACKGROUND Although preoperative and postoperative initiation of prophylaxis for deep vein thrombosis (DVT) with low-molecular-weight heparin (LMWH) are effective, the relative effectiveness and safety of these approaches is unknown. In the absence of a published definitive level 1 trial addressing this question, a meta-analysis is appropriate. OBJECTIVE To report a meta-analysis comparing preoperative with postoperative initiation of prophylaxis of DVT in patients undergoing elective hip… CONTINUE READING

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