Preoperative use of enoxaparin compared with unfractionated heparin increases the incidence of re-exploration for postoperative bleeding after open-heart surgery in patients who present with an acute coronary syndrome: clinical investigation and reports.

@article{Jones2002PreoperativeUO,
  title={Preoperative use of enoxaparin compared with unfractionated heparin increases the incidence of re-exploration for postoperative bleeding after open-heart surgery in patients who present with an acute coronary syndrome: clinical investigation and reports.},
  author={Heath U. Jones and Joseph Brent Muhlestein and Kent W Jones and Tami L. Bair and Farangis Lavasani and Mahtab Sohrevardi and Benjamin D. Horne and Donald B. Doty and Donald L. Lapp{\'e}},
  journal={Circulation},
  year={2002},
  volume={106 12 Suppl 1},
  pages={I19-22}
}
BACKGROUND Enoxaparin has become an attractive therapy for use during acute coronary syndrome (ACS) because of its potential superior efficacy over unfractionated heparin (UFH), its longer activity, and its subcutaneous route of administration. However, because a significant number of patients presenting with ACS may be sent directly to open heart surgery while still on anticoagulation, it is important to understand any potential bleeding risks that may be associated with the use of enoxaparin… CONTINUE READING
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