Preoperative treatment with recombinant human growth hormone prevents ischemia reperfusion-induced diaphragmatic dysfunction.

@article{Moneley2001PreoperativeTW,
  title={Preoperative treatment with recombinant human growth hormone prevents ischemia reperfusion-induced diaphragmatic dysfunction.},
  author={Daragh S. Moneley and Mary Claire Barry and R. McLaughlin and Cathal J. Kelly and David Bouchier Hayes},
  journal={The Journal of surgical research},
  year={2001},
  volume={97 1},
  pages={81-4}
}
BACKGROUND Respiratory complications continue to be a major cause of morbidity and mortality following major vascular surgery. The recent UK Small Aneurysm Trial cited preoperative respiratory function as the major predictor of outcome following elective aortic surgery. AIM The aim of this study was to investigate the effect of aortic clamping and revascularization on diaphragmatic muscle function in a small animal model and to evaluate the role of preoperative treatment with recombinant… CONTINUE READING