Preoperative radiation and chemotherapy in the treatment of adenocarcinoma of the rectum.

@article{Chari1995PreoperativeRA,
  title={Preoperative radiation and chemotherapy in the treatment of adenocarcinoma of the rectum.},
  author={Ravi S. Chari and Douglas S. Tyler and Mitchell Steven Anscher and Linda Kathleen Russell and Bryan M. Clary and James A. Hathorn and Hilliard F. Seigler},
  journal={Annals of surgery},
  year={1995},
  volume={221 6},
  pages={
          778-86; discussion 786-7
        }
}
OBJECTIVE In this study, the impact of preoperative chemotherapy and radiation on the histopathology of a subgroup of patients with rectal adenocarcinoma was examined. As well, survival, disease-free survival and pelvic recurrence rates were examined, and compared with a concurrent control group. SUMMARY BACKGROUND DATA The optimal treatment of large rectal carcinomas remains controversial; current therapy usually involves abdominoperineal resection plus postoperative chemoradiation; the… CONTINUE READING
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