Preoperative magnetic resonance and intraoperative ultrasound fusion imaging for real-time neuronavigation in brain tumor surgery.

@article{Prada2015PreoperativeMR,
  title={Preoperative magnetic resonance and intraoperative ultrasound fusion imaging for real-time neuronavigation in brain tumor surgery.},
  author={Francesco Prada and Massimiliano Del Bene and Luca Mattei and Luca Lodigiani and Stefano Debeni and V. Kolev and Ignazio Gaspare Vetrano and Luigi Alessandro Solbiati and Georgios Sakas and Francesco DiMeco},
  journal={Ultraschall in der Medizin},
  year={2015},
  volume={36 2},
  pages={
          174-86
        }
}
PURPOSE Brain shift and tissue deformation during surgery for intracranial lesions are the main actual limitations of neuro-navigation (NN), which currently relies mainly on preoperative imaging. Ultrasound (US), being a real-time imaging modality, is becoming progressively more widespread during neurosurgical procedures, but most neurosurgeons, trained on axial computed tomography (CT) and magnetic resonance imaging (MRI) slices, lack specific US training and have difficulties recognizing… 
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74 Citations
Background Citations
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Methods Citations
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Results Citations
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74 Citations

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Citation Type

A new application of ultrasound-magnetic resonance multimodal fusion virtual navigation in glioma surgery.
TLDR
Real-time UMNS is an effective, timesaving technology that offers high quality intraoperative imaging and injection markers between functional white matter fibers and tumor by UMNS can help to obtain a maximum EOR of glioma and functional protection postoperatively.
Advanced Ultrasound Imaging in Glioma Surgery: Beyond Gray-Scale B-mode
TLDR
An US-based multimodal approach for image-guidance in glioma surgery is presented, highlighting the different features of advanced US modalities: fusion imaging with pre-operative acquired MRI for Virtual Navigation, B-mode, Doppler, CEUS, and elastosonography.
Demonstrative study of brain anatomical landmarks by intraoperative ultrasound imaging
TLDR
Real-time ultrasound is of great help during brain surgeries in delineating brain anatomical landmarks as well as MRI, and CT brain and makes brain surgery more simple with avoiding brain shift problems, radiation exposure, and high cost of other intraoperative modalities.
Intraoperative Ultrasound: Emerging Technology and Novel Applications in Brain Tumor Surgery
TLDR
The role of IOUS is confirmed in maximizing the EOR, which is strictly associated with postoperative outcome, overall survival (OS), and patient’s quality of life (QoL), and the combination of ultrasound advanced techniques such as Doppler, color Dopplers, elastosonography, and contrast-enhanced intraoperative ultrasound (CEUS) is crucial to improve surgical effectiveness and patient's safety while expanding surgeon's view.
Real-Time Ultrasound-Guided Catheter Navigation for Approaching Deep-Seated Brain Lesions: Role of Intraoperative Neurosonography with and without Fusion with Magnetic Resonance Imaging
TLDR
The catheter insertion technique described here provides a quick, accurate, and safe method for reaching deep-seated brain lesions using real-time intraoperative ultrasound placement of a catheter to mark the dissection trajectory to the lesion.
Intraoperative Navigated Angiosonography for Skull Base Tumor Surgery.
Utilizing Intraoperative Navigated 3D Color Doppler Ultrasound in Glioma Surgery
TLDR
3D iUS color Doppler allows estimation of brain shift intraoperatively, thus increasing patient safety, and future implementation of the reconstructed vessel tree into the navigational setup might allow navigational updating with further consecutive increasement of accuracy.
Direct navigated 3D ultrasound for resection of brain tumors: a useful tool for intraoperative image guidance.
TLDR
It is demonstrated that 3D ultrasound can be effectively used as a stand-alone navigation modality during the resection of brain tumors and the ability to provide repeated, high-quality intraoperative updates is useful for guiding resection.
Navigated 3D Ultrasound in Brain Metastasis Surgery: Analyzing the Differences in Object Appearances in Ultrasound and Magnetic Resonance Imaging
TLDR
i3D US clearly delineates tumor boundaries and allows live updating of imaging for compensation of brain shift, which can already be identified to a significant amount before dural opening.
Integrated multi-modality image-guided navigation for neurosurgery: open-source software platform using state-of-the-art clinical hardware
TLDR
The present prototype IGS system was tailored for neurosurgery and met all minimum design requirements focused on skull base surgery and created an open-source software platform to integrate with readily available commercial hardware.
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