Preoperative levosimendan decreases mortality and the development of low cardiac output in high-risk patients with severe left ventricular dysfunction undergoing coronary artery bypass grafting with cardiopulmonary bypass.

@article{Levin2012PreoperativeLD,
  title={Preoperative levosimendan decreases mortality and the development of low cardiac output in high-risk patients with severe left ventricular dysfunction undergoing coronary artery bypass grafting with cardiopulmonary bypass.},
  author={Ricardo L. Levin and Marcela A Degrange and Carlos D del Mazo and Eduardo Tan{\'u}s and Rafael Porcile},
  journal={Experimental and clinical cardiology},
  year={2012},
  volume={17 3},
  pages={
          125-30
        }
}
BACKGROUND The calcium sensitizer levosimendan has been used in cardiac surgery for the treatment of postoperative low cardiac output syndrome (LCOS) and difficult weaning from cardiopulmonary bypass (CPB). OBJECTIVES To evaluate the effects of preoperative treatment with levosimendan on 30-day mortality, the risk of developing LCOS and the requirement for inotropes, vasopressors and intra-aortic balloon pumps in patients with severe left ventricular dysfunction. METHODS Patient with severe… CONTINUE READING

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