Preoperative levels of urinary uromodulin predict acute kidney injury after pediatric cardiopulmonary bypass surgery

@article{Bennett2017PreoperativeLO,
  title={Preoperative levels of urinary uromodulin predict acute kidney injury after pediatric cardiopulmonary bypass surgery},
  author={Michael R Bennett and Olivia Pyles and Qing Ma and Prasad Devarajan},
  journal={Pediatric Nephrology},
  year={2017},
  volume={33},
  pages={521-526}
}
Acute kidney injury (AKI) is a common complication of cardiopulmonary bypass surgery (CPB) in children. Several promising postoperative AKI biomarkers have been identified, but no preoperative biomarkers are available. We evaluated the association of urinary uromodulin (uUMOD) with postoperative AKI. One hundred and one children undergoing CPB were enrolled. Urine was collected prior to CPB, and AKI was defined as ≧50% increase in serum creatinine from preoperative baseline within 48 h of… CONTINUE READING
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