Preoperative lanreotide treatment improves outcome in patients with acromegaly resulting from invasive pituitary macroadenoma.

@article{Li2012PreoperativeLT,
  title={Preoperative lanreotide treatment improves outcome in patients with acromegaly resulting from invasive pituitary macroadenoma.},
  author={Zhengbang Li and Zhiwei Quan and H-L Tian and Matthew Cheng},
  journal={The Journal of international medical research},
  year={2012},
  volume={40 2},
  pages={
          517-24
        }
}
OBJECTIVE To investigate whether 3 months' preoperative treatment with lanreotide improved outcome in newly diagnosed patients with acromegaly resulting from invasive pituitary macroadenoma. METHODS After baseline evaluation, untreated patients were randomized to undergo direct transsphenoidal surgery or lanreotide treatment (30 mg via intramuscular injection every 2 weeks, increased to 30 mg/week at week 8 if growth hormone nadir > 2.5 μg/l), for 3 months prior to surgery. Tumour shrinkage… CONTINUE READING
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