Preoperative infusional chemoradiation therapy for stage T3 rectal cancer.

  title={Preoperative infusional chemoradiation therapy for stage T3 rectal cancer.},
  author={Tyvin A. Rich and John Michael Skibber and Jaffer A. Ajani and D J Buchholz and Karen R. Cleary and R. A. Dubrow and Bruce Levin and Patrick M. Lynch and Sarkis Meterissian and Leor D. Roubein},
  journal={International journal of radiation oncology, biology, physics},
  volume={32 4},
PURPOSE To evaluate preoperative infusional chemoradiation for patients with operable rectal cancer. METHODS AND MATERIALS Preoperative chemoradiation therapy using infusional 5-fluorouracil (5-FU), (300 mg/m2/day) together with daily irradiation (45 Gy/25 fractions/5 weeks) was administered to 77 patients with clinically Stage T3 rectal cancer. Endoscopic ultrasound confirmed the digital rectal exam in 63 patients. Surgery was performed approximately 6 weeks after the completion of… CONTINUE READING