Preoperative hyperthermia combined with radiochemotherapy in locally advanced rectal cancer: a phase II clinical trial.

@article{Rau1998PreoperativeHC,
  title={Preoperative hyperthermia combined with radiochemotherapy in locally advanced rectal cancer: a phase II clinical trial.},
  author={B. Shankar Rau and Peter Wust and Peter Hohenberger and J{\"u}rgen L{\"o}ffel and Michael H{\"u}nerbein and Cheryl Below and Johanna Gellermann and Andreia Speidel and Thomas J. Vogl and Hanno B Riess and Roland Felix and Peter M. Schlag},
  journal={Annals of surgery},
  year={1998},
  volume={227 3},
  pages={380-9}
}
OBJECTIVE A prospective phase II study was performed to determine the feasibility and efficacy in terms of response rate, resectability, and morbidity in patients with locally advanced rectal cancer who received preoperative regional hyperthermia combined with radiochemotherapy (HRCT). SUMMARY BACKGROUND DATA Recent studies suggest that preoperative radiochemotherapy in locally advanced rectal cancer can induce downstaging, but after resection the incidence of local recurrences remains high… CONTINUE READING

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