• DOI:10.3928/01477447-20150204-56
• Corpus ID: 9705137

Preoperative embolization for bone metastasis from hepatocellular carcinoma.

@article{Kim2015PreoperativeEF,
  title={Preoperative embolization for bone metastasis from hepatocellular carcinoma.},
  author={Wanlim Kim and Ilkyu Han and Hwan Jun Jae and Seungcheol Kang and Sang A Lee and Jong Seop Kim and Han-Soo Kim},
  journal={Orthopedics},
  year={2015},
  volume={38 2},
  pages={
          e99-e105
        }
}

• Wanlim Kim, I. Han, +4 authors Han-Soo Kim
• Published 1 February 2015
• Medicine
• Orthopedics

Preoperative transcatheter arterial embolization for hypervascular bone tumors is now widely accepted as a safe and effective procedure for reducing intraoperative blood loss and surgical morbidity. However, few studies have reported the use of preoperative transcatheter arterial embolization for nonspine bone metastases from hepatocellular carcinoma. The goal of this study was to assess the effect of preoperative embolization on blood loss and clinical outcomes in surgery for nonspine bone metastasis from hepatocellular carcinoma. Seventy-five patients with metastases from hepatocellular carcinoma to the pelvis and extremities were reviewed retrospectively. The study population consisted of 62 men and 13 women, with a mean age of 64.6 years (range, 40.0-80.1). The average follow-up period was 8.2 months (range, 0.3-66.1). Twenty-two patients underwent transcatheter arterial embolization for preoperative devascularization (group A), and 53 patients underwent operative treatment only (group B). The proportion of pelvis metastases was significantly higher (P<.001) and operative time was longer (P=.006) in group A than in group B. However, a significantly smaller decrease in hemoglobin level before and after surgery was seen in group A (P=.017). No significant differences were seen in intraoperative estimated blood loss, perioperative hemoglobin level, number of allogeneic transfusions, or length of hospitalization between the 2 groups. Preoperative transcatheter arterial embolization is an effective means to reduce bleeding during surgery for nonspine metastases from hepatocellular carcinoma. In general, surgical procedures that included transcatheter arterial embolization took longer and were more extensive.