Preoperative chemotherapy in advanced resectable head and neck cancer: final report of the Southwest Oncology Group.

@article{Schuller1988PreoperativeCI,
  title={Preoperative chemotherapy in advanced resectable head and neck cancer: final report of the Southwest Oncology Group.},
  author={David E. Schuller and Barbara Metch and D. W. J. Stein and Douglas Ernest Mattox and Joseph D. McCracken},
  journal={The Laryngoscope},
  year={1988},
  volume={98 11},
  pages={1205-11}
}
In 1980, the Southwest Oncology Group instituted a multi-institutional, prospective, randomized phase III trial to evaluate whether inductive chemotherapy improved survival in patients with advanced stage resectable squamous cell carcinoma of the head and neck. From a group of 158 eligible patients, 76 were randomized to conventional treatment (surgery and postoperative radiotherapy), and 82 were assigned to experimental treatment (induction chemotherapy, surgery, postoperative radiotherapy… CONTINUE READING