Preoperative chemoradiotherapy and radical surgery for locally advanced distal rectal adenocarcinoma: pathologic findings and clinical implications.

@article{Medich2001PreoperativeCA,
  title={Preoperative chemoradiotherapy and radical surgery for locally advanced distal rectal adenocarcinoma: pathologic findings and clinical implications.},
  author={David S. Medich and Joe McGinty and David S Parda and Sonja Karlovits and Charles D Davis and Philip F. Caushaj and Barry C. Lembersky},
  journal={Diseases of the colon and rectum},
  year={2001},
  volume={44 8},
  pages={1123-8}
}
PURPOSE Preoperative chemoradiotherapy followed by radical surgical resection has been the preferred treatment for patients presenting with locally advanced distal rectal carcinoma at our institutions. We postulated that chemoradiotherapy-induced pathologic response of the primary tumor would identify which patients would be candidates for local excision as definitive surgical therapy. METHODS A retrospective analysis of 60 patients with palpable, locally advanced, distal rectal… CONTINUE READING

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