Preoperative carcinoembryonic antigen level as a prognostic indicator in colorectal cancer.

@article{Wanebo1978PreoperativeCA,
  title={Preoperative carcinoembryonic antigen level as a prognostic indicator in colorectal cancer.},
  author={Harold J. Wanebo and Bobby S. Rao and Carl M. Pinsky and Raymond G. Hoffman and Mona Stearns and Morton K. Schwartz and Herbert Friedrich Oettgen},
  journal={The New England journal of medicine},
  year={1978},
  volume={299 9},
  pages={
          448-51
        }
}
We examined the relation of carcinoembryonic antigen levels to time, site and extent of recurrence in 358 patients with colorectal cancer. The recurrence rate was higher in patients with Dukes' B and Dukes' C lesions who had preoperative levels higher than 5 ng per milliliter. There was a linear inverse correlation between preoperative levels and estimated mean time to recurrence in patients with Dukes' B and C lesions, ranging from 30 months for a level of 2 to 9.8 months for a level of 70 ng… CONTINUE READING
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