Preoperative Serum Caveolin-1 as a Prognostic Marker for Recurrence in a Radical Prostatectomy Cohort

  title={Preoperative Serum Caveolin-1 as a Prognostic Marker for Recurrence in a Radical Prostatectomy Cohort},
  author={Salahaldin A. Tahir and A. Frolov and T. Hayes and M. Mims and B. Miles and S. Lerner and T. Wheeler and G. Ayala and T. Thompson and D. Kadmon},
  journal={Clinical Cancer Research},
  pages={4872 - 4875}
  • Salahaldin A. Tahir, A. Frolov, +7 authors D. Kadmon
  • Published 2006
  • Medicine
  • Clinical Cancer Research
  • Purpose: Up-regulation of caveolin-1 (cav-1) is associated with virulent prostate cancer, and serum cav-1 levels are elevated in prostate cancer patients but not in benign prostatic hyperplasia. In this study, we evaluated the potential of high preoperative serum cav-1 levels to predict biochemical progression of prostate cancer. The value of the combined preoperative markers, prostate-specific antigen (PSA), biopsy Gleason score, and serum cav-1 for predicting biochemical recurrence was also… CONTINUE READING

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