Preoperative Isolated Limb Infusion of Doxorubicin and External Irradiation for Limb-Threatening Soft Tissue Sarcomas

@article{Hegazy2006PreoperativeIL,
  title={Preoperative Isolated Limb Infusion of Doxorubicin and External Irradiation for Limb-Threatening Soft Tissue Sarcomas},
  author={Mohamed Abdel Fattah Hegazy and Sherif Z. Kotb and Hanem A. Sakr and Ebrahim El Dosoky and Talal Ahmed Amer and Refaat A. F. Hegazi and Omar Farouk},
  journal={Annals of Surgical Oncology},
  year={2006},
  volume={14},
  pages={568-576}
}
At present, limb-sparing surgery is the most appropriate and acceptable treatment option for soft tissue sarcomas of the extremities. To increase the number of limb-sparing resections in the treatment of locally advanced soft tissue sarcomas of the extremities, preoperative radiotherapy and/or chemotherapy are often used. Isolated limb perfusion of cytostatic agents is an effective alternative option but technically complex. Isolated limb infusion, essentially a low-flow isolated limb perfusion… CONTINUE READING

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