Prenyltransferases as key enzymes in primary and secondary metabolism

@article{Winkelblech2015PrenyltransferasesAK,
  title={Prenyltransferases as key enzymes in primary and secondary metabolism},
  author={Julia Winkelblech and Aili Fan and Shu-Ming Li},
  journal={Applied Microbiology and Biotechnology},
  year={2015},
  volume={99},
  pages={7379-7397}
}
Attachment of isoprene units to various acceptors by prenylation plays an important role in primary and secondary metabolism of living organisms. Protein prenylation belongs to posttranslational modification and is involved in cellular regulation process. Prenylated secondary metabolites usually demonstrate promising biological and pharmacological activities. Prenyl transfer reactions catalyzed by prenyltransferases represent the key steps in the biosynthesis and contribute significantly to the… CONTINUE READING
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