Prenyltransferase. Product binding and reaction termination.

Abstract

Prenyltransferase catalyzes the condensation of an allylic pyrophosphate with isopentenyl pyrophosphate, producing the next higher homologue of the substrate. Thus, the product of prenyltransferase is an allylic pyrophosphate and hence a potential substrate for further condensation. The product of the prenyltransferase of sterol biosynthesis, farnesyl… (More)

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