Prenatally undernourished rats show increased preference for wheel running v. lever pressing for food in a choice task
@article{Miles2008PrenatallyUR,
title={Prenatally undernourished rats show increased preference for wheel running v. lever pressing for food in a choice task},
author={Jennifer L Miles and Jason Landon and Michael Davison and Christian U. Kr{\"a}geloh and Nichola M. Thompson and Christopher M. Triggs and Bernhard H Breier},
journal={British Journal of Nutrition},
year={2008},
volume={101},
pages={902 - 908}
}Maternal nutrition during pregnancy has a significant influence in establishing patterns of metabolism and postnatal behaviours in offspring, and therefore shapes their risk of developing disorders in later life. Although it is well established that a mismatch between food consumption and energy expenditure leads to obesity and metabolic dysregulation, little research has investigated the biological origin of such behaviour. We conducted the present experiments to investigate effects of early…
28 Citations
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In humans a suboptimal diet during development has negative outcomes in offspring. We investigated the behavioral outcomes in baboons born to mothers undergoing moderate maternal nutrient restriction…
Late-onset exercise in female rat offspring ameliorates the detrimental metabolic impact of maternal obesity.
- Biology, MedicineEndocrinology
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Late-onset exercise ameliorated the effects of maternal obesity and postweaning HFD in reducing body weight, adiposity, plasma leptin, insulin, triglycerides, and glucose intolerance, with greater beneficial effects in offspring of obese dams.
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- BiologyObesity reviews : an official journal of the International Association for the Study of Obesity
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It is found that lower protein content of restricted diets is associated with higher food intake in female offspring, and that a main source of variation among studies arises from whether, and how, food intake was adjusted for body mass.
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- Biology, MedicineEndocrinology
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The data suggest that IUGR offspring have increased flexibility of energy storage and use and that moderate daily exercise prevents obesity development through activation of distinct pathways of energy use.
Exercise in obese female rats has beneficial effects on maternal and male and female offspring metabolism
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MEx before and during pregnancy has beneficial effects on the maternal and offspring metabolism and endocrine function occurring with no weight change in mothers and offspring indicating the importance of body composition rather than weight in evaluations of metabolic status.
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Possibility of introducing significant modifications of the programming of the offspring’s desirable development and health status by adequate and physiological maternal exercise during pregnancy was supported also by some observations in humans.
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