Prenatal ultrasound detection of isolated neural tube defects: is cytogenetic evaluation warranted?


OBJECTIVE To determine the value of cytogenetic evaluation in fetuses with isolated neural tube defects diagnosed by prenatal ultrasound. METHODS Fifty-five thousand two hundred sixty obstetric ultrasounds performed for various indications at the Indiana University Prenatal Diagnostic Center from July 1988 to March 1994 were reviewed using a computerized… (More)