Prenatal testosterone excess reduces sperm count and motility.

  title={Prenatal testosterone excess reduces sperm count and motility.},
  author={Sergio E. Recabarren and Pedro P. Rojas-Garc{\'i}a and M{\'o}nica P. Recabarren and Victor H Alfaro and Rosita Smith and Vasantha Padmanabhan and Teresa Sir-Petermann},
  volume={149 12},
The reproductive system is extremely susceptible to insults from exposure to exogenous steroids during development. Excess prenatal testosterone exposure programs neuroendocrine, ovarian, and metabolic deficits in the female, features seen in women with polycystic ovary disease. The objective of this study was to determine whether prenatal testosterone excess also disrupts the male reproductive system, using sheep as a model system. The extent of reproductive disruption was tested by assessing… CONTINUE READING


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