Prenatal stress selectively alters the reactivity of the hypothalamic-pituitary adrenal system in the female rat

@article{Weinstock1992PrenatalSS,
  title={Prenatal stress selectively alters the reactivity of the hypothalamic-pituitary adrenal system in the female rat},
  author={Marta Weinstock and E. A. Matlina and G. Maor and Haim Rosen and Bruce S. McEwen},
  journal={Brain Research},
  year={1992},
  volume={595},
  pages={195-200}
}

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TLDR
The present experiments failed to reveal a decrease in hedonic behavior in prenatally stressed rats, and observed changes in hormone and CRH mRNA levels indicate that the gestational stress used did not result in a depression-like state in adult offspring.

Mild Prenatal Stress Causes Emotional and Brain Structural Modifications in Rats of Both Sexes

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It is shown that stressful events during pregnancy can lead to long-lasting structural and neurochemical effects in the offspring, which affect behavior in adulthood.

Differential adaptive responses to chronic stress of maternally stressed male mice offspring.

TLDR
Exposure to maternal stress in the womb can affect an animal's coping capacity to chronic postnatal stress, and it was demonstrated that a dysfunction in negative feedback inhibition of the HPA axis could be deteriorated by chronic stress in maternally stressed male mice.

Prenatal stress alters circadian activity of hypothalamo-pituitary-adrenal axis and hippocampal corticosteroid receptors in adult rats of both gender.

TLDR
Results show that prenatally stressed rats exhibit an altered temporal functioning of the HPA axis, which reinforces the idea of a general homeostatic dysfunction in those animals, and could be mediated by a reduction in corticosteroid receptors at specific times of day.

Sexually dimorphic effects of prenatal stress on cognition, hormonal responses, and central neurotransmitters.

TLDR
Data reinforce the view that prenatal stress affects multiple aspects of brain development, interfering with the expression of normal behavioral, neuroendocrine, and neurochemical sex differences, and implications for the effects of prenatal stress on the development of sexually dimorphic endocrine and neurological disorders.
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