Prenatal stress alters cardiovascular responses in adult rats.

  title={Prenatal stress alters cardiovascular responses in adult rats.},
  author={Natalia B. Igosheva and Olesya A. Klimova and Tatyana Anishchenko and Vivette Glover},
  journal={The Journal of physiology},
  volume={557 Pt 1},
Environmental factors in early life are clearly established risk factors for cardiovascular disease in later life. Most studies have focused on nutritional programming and analysed basal cardiovascular parameters rather than responses. In the present study we have investigated whether prenatal stress has long-term effects on cardiovascular responses in adult offspring. Female pregnant Sprague-Dawley rats were subjected to stress three times daily from day 15 to day 21 of gestation. Litters from… CONTINUE READING

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