Prenatal screening for trisomy 21: recent advances and guidelines

@inproceedings{Canick2012PrenatalSF,
  title={Prenatal screening for trisomy 21: recent advances and guidelines},
  author={J. Canick},
  booktitle={Clinical chemistry and laboratory medicine},
  year={2012}
}
  • J. Canick
  • Published in
    Clinical chemistry and…
    2012
  • Medicine
  • Abstract The performance of prenatal screening tests for the identification of trisomy 21 (Down syndrome) has markedly improved since the 1970s and early 1980s when maternal age was the sole mode of screening the general pregnant population. With the discovery of second trimester serum markers in the 1980s and 1990s and implementation of double, triple, and quad marker testing; the discovery of first trimester serum and ultrasound markers in the 1990s and implementation of the combined test… CONTINUE READING
    22 Citations

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