Prenatal screening for trisomy 21: recent advances and guidelines
@inproceedings{Canick2012PrenatalSF, title={Prenatal screening for trisomy 21: recent advances and guidelines}, author={J. Canick}, booktitle={Clinical chemistry and laboratory medicine}, year={2012} }
Abstract The performance of prenatal screening tests for the identification of trisomy 21 (Down syndrome) has markedly improved since the 1970s and early 1980s when maternal age was the sole mode of screening the general pregnant population. With the discovery of second trimester serum markers in the 1980s and 1990s and implementation of double, triple, and quad marker testing; the discovery of first trimester serum and ultrasound markers in the 1990s and implementation of the combined test… CONTINUE READING
Supplemental Presentations
Figures, Tables, and Topics from this paper
22 Citations
First trimester, second trimester, and integrated screening for Down's syndrome in China
- Medicine
- Journal of medical screening
- 2012
- 10
Noninvasive Fetal Trisomy (NIFTY) test: an advanced noninvasive prenatal diagnosis methodology for fetal autosomal and sex chromosomal aneuploidies
- Biology, Medicine
- BMC Medical Genomics
- 2011
- 117
- PDF
An Overview on Prenatal Screening for Chromosomal Aberrations
- Biology, Medicine
- Journal of laboratory automation
- 2015
- 7
Non-invasive prenatal testing: impact on invasive prenatal diagnosis at a mainland Chinese tertiary medical center
- Medicine
- The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians
- 2016
- 12
Triploidy and Routine Combined First Trimester Pregnancy Screening
- Medicine
- Avicenna journal of medical biotechnology
- 2019
- 1
- PDF
Chorionic villus sampling for early prenatal diagnosis: Experience at a mainland Chinese hospital
- Medicine
- Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology
- 2014
- 8
Non-invasive prenatal diagnostics of aneuploidy using next-generation DNA sequencing technologies, and clinical considerations
- Medicine, Biology
- Clinical chemistry and laboratory medicine
- 2013
- 20
- PDF
Performance of prenatal screening using maternal serum and ultrasound markers for Down syndrome in Chinese women: a systematic review and meta‐analysis
- Medicine
- BJOG : an international journal of obstetrics and gynaecology
- 2016
- 7
Laboratory maternal-fetal medicine: challenges and perspectives
- Medicine
- Clinical chemistry and laboratory medicine
- 2012
- PDF
References
SHOWING 1-10 OF 19 REFERENCES
Prenatal screening for fetal aneuploidy.
- Medicine
- Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC
- 2007
- 19
Integrated screening for Down's syndrome based on tests performed during the first and second trimesters.
- Medicine
- The New England journal of medicine
- 1999
- 441
Comparing Three Screening Strategies for Combining First- and Second-Trimester Down Syndrome Markers
- Medicine
- Obstetrics and gynecology
- 2006
- 56
- PDF
Epidemiologic monitoring of prenatal screening for neural tube defects and Down syndrome.
- Medicine
- Clinics in laboratory medicine
- 2003
- 26
First-trimester or second-trimester screening, or both, for Down's syndrome.
- Medicine
- The New England journal of medicine
- 2005
- 501
- PDF
MATERNAL SERUM ALPHA-FETOPROTEIN MEASUREMENT: A SCREENING TEST FOR DOWN SYNDROME
- Medicine
- The Lancet
- 1984
- 396
An association between low maternal serum alpha-fetoprotein and fetal chromosomal abnormalities.
- Medicine
- American journal of obstetrics and gynecology
- 1984
- 192
A model for disclosing the first trimester part of an integrated Down's syndrome screening test
- Biology, Medicine
- Clinical genetics
- 2004
- 15