Prenatal screening for fetal aneuploidies with cell-free DNA in the general pregnancy population: a cost-effectiveness analysis.

@article{Fairbrother2016PrenatalSF,
  title={Prenatal screening for fetal aneuploidies with cell-free DNA in the general pregnancy population: a cost-effectiveness analysis.},
  author={Genevieve L Fairbrother and John Burigo and Thomas A. Sharon and Ken Song},
  journal={The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians},
  year={2016},
  volume={29 7},
  pages={
          1160-4
        }
}
OBJECTIVE To estimate the cost-effectiveness of fetal aneuploidy screening in the general pregnancy population using non-invasive prenatal testing (NIPT) as compared to first trimester combined screening (FTS) with serum markers and NT ultrasound. METHODS Using a decision-analytic model, we estimated the number of fetal T21, T18, and T13 cases identified prenatally, the number of invasive procedures performed, corresponding normal fetus losses, and costs of screening using FTS or NIPT with… CONTINUE READING

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Has Noninvasive Prenatal Testing (NIPT) Come of Age?

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