Prenatal famine exposure, health in later life and promoter methylation of four candidate genes.

@article{Veenendaal2012PrenatalFE,
  title={Prenatal famine exposure, health in later life and promoter methylation of four candidate genes.},
  author={Marjolein V E Veenendaal and Paula M Costello and K. A. Lillycrop and S R de Rooij and J.A.M. van der Post and Patrick M Bossuyt and Mark A. Hanson and R C Painter and Tessa J. Roseboom},
  journal={Journal of developmental origins of health and disease},
  year={2012},
  volume={3 6},
  pages={
          450-7
        }
}
  • Marjolein V E Veenendaal, Paula M Costello, +6 authors Tessa J. Roseboom
  • Published in
    Journal of developmental…
    2012
  • Biology, Medicine
  • Poor nutrition during fetal development can permanently alter growth, cardiovascular physiology and metabolic function. Animal studies have shown that prenatal undernutrition followed by balanced postnatal nutrition alters deoxyribonucleic acid (DNA) methylation of gene promoter regions of candidate metabolic control genes in the liver. The aim of this study was to investigate whether methylation status of the proximal promoter regions of four candidate genes differed between individuals… CONTINUE READING

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