Prenatal exposure to high galactose adversely affects initial gonadal pool of germ cells in rats.


BACKGROUND In rats, prenatal exposure to high concentrations of galactose may contribute to a condition that is equivalent to the premature ovarian failure (POF) component of human galactosaemia. We investigated if development of POF under experimental galactosaemia-like conditions was attributed to impaired germ cell migration. METHODS Pregnant rats were… (More)


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