Prenatal exposure to cocaine. I: Effects on gestation, development, and activity in Sprague-Dawley rats.

@article{Johns1992PrenatalET,
  title={Prenatal exposure to cocaine. I: Effects on gestation, development, and activity in Sprague-Dawley rats.},
  author={Josephine M. Johns and Larry W. Means and M J Means and Brian A. McMillen},
  journal={Neurotoxicology and teratology},
  year={1992},
  volume={14 5},
  pages={337-42}
}
Sperm-positive Sprague-Dawley rats received one of four treatments for 20 days beginning within 24 hours of conception. One group received subcutaneous injections of 15 mg/kg cocaine twice daily (Cocaine-D); a second group received 15 mg/kg cocaine twice daily for two consecutive days at 5-day intervals (Cocaine-I); a third group received normal saline twice daily (Saline); and a fourth group received 1.5 mg/kg amfonelic acid (AFA), a dopamine reuptake inhibitor, once daily. Cocaine-D, Cocaine… CONTINUE READING

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