Prenatal diagnosis of lissencephaly: A case report

@article{Aslan2009PrenatalDO,
  title={Prenatal diagnosis of lissencephaly: A case report},
  author={Halil Aslan and Kemal Gungorduk and Doğukan Yıldırım and Oğuz Aslan and Gokhan Yildirim and Yavuz Ceylan},
  journal={Journal of Clinical Ultrasound},
  year={2009},
  volume={37}
}
We describe the abnormal sonographic findings in the brain of a 26‐week fetus, which increased the suspicion of isolated lissencephaly. Follow‐up ultrasound examination and MRI depicted diffuse cortical agyria, microcephaly, hypotelorism, and proptosis. Cordocentesis showed a normal 46,XY karyotype, and no short arm deletion of chromosome 17 was detectable. Postmortem examination confirmed complete agyria of the whole fetal brain. Early detection of fetal microcephaly and other cranial… Expand
Prenatal Diagnosis of Isolated Lissencephaly by Ultrasonography and Magnetic Resonance Imaging: A Case Report
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The abnormal sonographic findings in the brain of a 26-week fetus of a woman with a history of prednisolone use in early pregnancy, which increased the suspicion of isolated lissencephaly, were presented. Expand
Re: Prenatal diagnosis of lissencephaly: A case report
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In this case, findings were subtle on MR performed at 24 weeks, but were well seen on repeat MR done at 34 weeks, which revealed abnormal flat insula, smooth brain parenchyma suggestive of lack of sulcation (Figure 1). Expand
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Prenatal diagnosis of monosomy 17p (17p13.3-->pter) associated with polyhydramnios, intrauterine growth restriction, ventriculomegaly, and Miller-Dieker lissencephaly syndrome in a fetus.
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Polyhydramnios, IUGR and ventriculomegaly are important prenatal ultrasound markers of MDLS and prenatal diagnosis of these markers should include a detailed investigation of cerebral sulci and fissures, and genetic analysis for MDLS. Expand
PICTORIAL ESSAY OF LISSENCEPHALY ON CT AND MRI
Lissencephaly, is a rare, gene-linked brain malformation characterized by the absence of normal convolutions (folds) in the cerebral cortex and an abnormally small head (microcephaly). In the usualExpand

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