Prenatal diagnosis of aneuploidies in amniotic fluid by multiple ligation-dependent probe amplification (MLPA) analysis.

@article{Hamidah2014PrenatalDO,
  title={Prenatal diagnosis of aneuploidies in amniotic fluid by multiple ligation-dependent probe amplification (MLPA) analysis.},
  author={N H Hamidah and A R Munirah and Alauddin Hafiza and A R Farisah and Ahmad Shuhaila and M N Norzilawati and Mohammed Yaacob Jamil and Othman Ainoon},
  journal={The Malaysian journal of pathology},
  year={2014},
  volume={36 3},
  pages={163-8}
}
Prenatal diagnosis is essential in the new era of diagnosis and management of genetic diseases in obstetrics. Multiple ligation-dependent probe amplification (MLPA) is a recent technique for prenatal diagnosis for the relative quantification of 40 different nucleic acid sequences in one single reaction. We had utilized the MLPA technique in detecting aneuploidies in amniotic fluid samples from 25 pregnant women from the Obstetrics and Gynaecology Department UKMMC, versus the quantitative… CONTINUE READING

References

Publications referenced by this paper.
Showing 1-10 of 14 references

Rapid detection of chromosomal aneuploidies in uncultured amniocytes by multiplex ligationdependent probe amplification (MLPA)

  • R Hochstenbach, J Meijer, J van den Brug
  • Prenat Diagn
  • 2005
Highly Influential
4 Excerpts

Forensic DNA typing. 2ed

  • JM Butler
  • 2005
1 Excerpt

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