Prenatal diagnosis of alpha-1-antitrypsin deficiency by PCR of linked polymorphisms: a study of 17 cases.

@article{Abbott1992PrenatalDO,
  title={Prenatal diagnosis of alpha-1-antitrypsin deficiency by PCR of linked polymorphisms: a study of 17 cases.},
  author={Catherine M. Abbott and Jennifer U Lovegrove and David B. Whitehouse and David A. Hopkinson and Sue Povey},
  journal={Prenatal diagnosis},
  year={1992},
  volume={12 4},
  pages={235-40}
}
We describe our experiences of prenatal diagnosis of alpha-1-antitrypsin deficiency using closely linked polymorphisms detected by Southern blotting and the polymerase chain reaction. Prenatal diagnosis was carried out for 17 pregnancies from 15 couples.