Prenatal diagnosis of β-thalassemia in Southern China

@inproceedings{Li2006PrenatalDO,
  title={Prenatal diagnosis of β-thalassemia in Southern China},
  author={Dong-Zhi Li and Can Liao and Jian Li and Xingmei Xie and Yining Huang and Hui-zhu Zhong and Jiaxue Wei},
  year={2006}
}
Abstract Objective To control the birth of thalassemic children in Southern China. Study design DNA-based diagnosis was offered on fetal tissues in pregnancies when β-globin gene mutations were identifiable in both parents using polymerase chain reaction (PCR)-reverse dot blot (RDB) assay. An automated high-performance liquid chromatography (HPLC) system was used to analyze fetal hemoglobin in pregnancies when mutation was unidentified in at least one parent. Fetal samplings were collected by… CONTINUE READING

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