Prenatal cocaine exposure disrupts the development of the serotonergic system

  title={Prenatal cocaine exposure disrupts the development of the serotonergic system},
  author={Homayoon M Akbari and H Kenneth Kramer and Patricia Mack Whitaker-Azmitia and Linda Patia Spear and Efrain Charles Azmitia},
  journal={Brain Research},
Prenatal cocaine exposure has been found to result in a number of neurobehavioral abnormalities in both clinical and laboratory studies. We have previously shown that cocaine inhibits the growth of developing serotonin neurons in culture. This study examines the effects of cocaine on the developing serotonin system in vivo. Pregnant rats were injected with cocaine (40 mg/kg s.c.) from gestational day 13 to parturition. One group of rats was additionally injected on postnatal days 1-5 with… CONTINUE READING

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