Prenatal carbocyanine dye tracing of septo-hypothalamic connections.

  title={Prenatal carbocyanine dye tracing of septo-hypothalamic connections.},
  author={Irina G. Makarenko},
  journal={Brain research},
  volume={1130 1},
This is the first study of the prenatal development of septal projections to the hypothalamus in rats, using carbocyanine dyes (DiI and DiA) as retrograde tracers. First septal neurons send axons to the preoptic area and anterior hypothalamus on embryonic day 14,5 (E14,5) and on E15 numerous labeled neurons are visualized in the septum after DiI insertion into the preoptic region. On E18 and E20 these neurons develop numerous spiny dendrites that occupy all rostrocaudal extension of the septum… CONTINUE READING