Prenatal androgen excess programs metabolic derangements in pubertal female rats.

@article{Yan2013PrenatalAE,
  title={Prenatal androgen excess programs metabolic derangements in pubertal female rats.},
  author={Xiaonan Yan and X Dai and Jing Wang and N Zhao and Yugui Cui and Jiayin Liu},
  journal={The Journal of endocrinology},
  year={2013},
  volume={217 1},
  pages={119-29}
}
Owing to the heterogeneity in the clinical symptoms of polycystic ovary syndrome (PCOS), the early pathophysiological mechanisms of PCOS remain unclear. Clinical, experimental, and genetic evidence supports an interaction between genetic susceptibility and the influence of maternal environment in the pathogenesis of PCOS. To determine whether prenatal androgen exposure induced PCOS-related metabolic derangements during pubertal development, we administrated 5α-dihydrotestosterone (DHT) in… CONTINUE READING

Citations

Publications citing this paper.
Showing 1-10 of 12 extracted citations

References

Publications referenced by this paper.
Showing 1-10 of 48 references

Similar Papers

Loading similar papers…