Prenatal administration of retinoic acid upregulates connective tissue growth factor in the nitrofen CDH model

@article{Ruttenstock2010PrenatalAO,
  title={Prenatal administration of retinoic acid upregulates connective tissue growth factor in the nitrofen CDH model},
  author={Elke Maria Ruttenstock and Takashi Doi and Jens Dingemann and Prem Puri},
  journal={Pediatric Surgery International},
  year={2010},
  volume={27},
  pages={573-577}
}
  • Elke Maria Ruttenstock, Takashi Doi, +1 author Prem Puri
  • Published in
    Pediatric Surgery…
    2010
  • Medicine
  • PurposeRecent studies have suggested that retinoids may be involved in the molecular mechanisms of pulmonary hypoplasia (PH) in congenital diaphragmatic hernia (CDH). Connective tissue growth factor (CTGF) plays a key role in foetal lung development and remodelling during later gestation. CTGF knockout mice exhibit PH with similar characteristics to the human and nitrofen-induced PH. Prenatal administration of retinoic acid (RA) has been shown to stimulate alveologenesis in nitrofen-induced PH… CONTINUE READING

    Create an AI-powered research feed to stay up to date with new papers like this posted to ArXiv

    Citations

    Publications citing this paper.
    SHOWING 1-6 OF 6 CITATIONS

    References

    Publications referenced by this paper.
    SHOWING 1-10 OF 25 REFERENCES

    Pulmonary hypoplasia in the connective tissue growth factor (Ctgf) null mouse.

    VIEW 5 EXCERPTS
    HIGHLY INFLUENTIAL

    Retinoic acid induces TGFb-dependent autocrine fribroblast growth

    • A Fadloun, D Kobi, L Delacroix
    • Oncogene
    • 2008
    VIEW 7 EXCERPTS
    HIGHLY INFLUENTIAL