Prenatal Exposure to Carbamazepine Reduces Hippocampal and Cortical Neuronal Cell Population in New-Born and Young Mice without Detectable Effects on Learning And Memory

@article{berg2013PrenatalET,
  title={Prenatal Exposure to Carbamazepine Reduces Hippocampal and Cortical Neuronal Cell Population in New-Born and Young Mice without Detectable Effects on Learning And Memory},
  author={E. {\AA}berg and S. Holst and A. Neagu and S. O. Ögren and C. Lavebratt},
  journal={PLoS ONE},
  year={2013},
  volume={8}
}
  • E. Åberg, S. Holst, +2 authors C. Lavebratt
  • Published 2013
  • Medicine
  • PLoS ONE
  • Pregnant women with epilepsy have to balance maternal and fetal risks associated with uncontrolled seizures against the potential teratogenic effects from antiepileptic drugs (AEDs). Carbamazepine (CBZ) is among the four most commonly used AEDs for treatment of pregnant epileptic women. We previously reported that new-born children had a decreased head circumference after in utero CBZ exposure. This study investigates how prenatal exposure of CBZ influences the number of neurons in new-born and… CONTINUE READING
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