Prenatal Diethylstilbestrol Exposure and Risk of Breast Cancer

  title={Prenatal Diethylstilbestrol Exposure and Risk of Breast Cancer},
  author={Julie R. Palmer and Lauren Anne Wise and Elizabeth E. Hatch and Rebecca Troisi and Linda T. Titus-Ernstoff and William C. Strohsnitter and Raymond H. Kaufman and Arthur L. Herbst and Kenneth L. Noller and Marianne Hyer and Robert N. Hoover},
  journal={Cancer Epidemiology Biomarkers \& Prevention},
  pages={1509 - 1514}
It has been hypothesized that breast cancer risk is influenced by prenatal hormone levels. Diethylstilbestrol (DES), a synthetic estrogen, was widely used by pregnant women in the 1950s and 1960s. Women who took the drug have an increased risk of breast cancer, but whether risk is also increased in the daughters who were exposed in utero is less clear. We assessed the relation of prenatal DES exposure to risk of breast cancer in a cohort of DES-exposed and unexposed women followed since the… 

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