Premotor and nonmotor features of Parkinson's disease.

  title={Premotor and nonmotor features of Parkinson's disease.},
  author={Jennifer G Goldman and Ron Postuma},
  journal={Current opinion in neurology},
  volume={27 4},
PURPOSE OF REVIEW This review highlights recent advances in premotor and nonmotor features in Parkinson's disease, focusing on these issues in the context of prodromal and early-stage Parkinson's disease. RECENT FINDINGS Although Parkinson's disease patients experience a wide range of nonmotor symptoms throughout the disease course, studies demonstrate that nonmotor features are not solely a late manifestation. Indeed, disturbances of smell, sleep, mood, and gastrointestinal function may… CONTINUE READING