Premonitory sensory phenomenon in Tourette's syndrome
@article{Kwak2003PremonitorySP, title={Premonitory sensory phenomenon in Tourette's syndrome}, author={Carolyn Kwak and Kevin Dat Vuong and Joseph Jankovic}, journal={Movement Disorders}, year={2003}, volume={18} }
We administered a questionnaire designed to probe for premonitory sensations associated with motor tics to 50 patients with Tourette's syndrome (TS). Premonitory sensations were reported by 46 (92%) patients, and the most common sensation was an urge to move and an impulse to tic (“had to do it”). Intensification of premonitory sensations, if prevented from performing a motor tic, was reported also in 37 patients (74%), 36 patients (72%) reported relief of premonitory sensations after…
239 Citations
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The simultaneous presence of both voluntary and involuntary aspects in the expression of tic symptoms by patients with TS is consistent with the hypothesis that tics can have the same neurophysiologic substrate as voluntary acts, even though they are misperceived as being involuntary.
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This article reviews the existing literature on the clinical and neurobiological aspects of the premonitory urge in patients with TS, with focus on its pathophysiology and possible treatment implications.
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Based on the concept that the premonitory urge induces tics, behavioral treatments such as Exposure and Response Prevention and Habit Reversal Therapy have been developed, but it is still unclear whether habituation, the main mechanism of these therapies, is directly related to their effectiveness.
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A systematic literature review of the published studies addressing the pathophysiological mechanisms of premonitory urges identified some preliminary evidence for specific alterations in sensorimotor processing at both cortical and subcortical levels.
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- 2015
The results suggest the the Italian translation of the PUTS has good psychometric properties, and a statistical significant correlation between PUTs score and obsessive-compulsive symptoms (OCS) at both interviews.
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Patients with TS exhibit increased PBC in addition to inhibitory deficits and complex interplay between neuropsychological and neurophysiological mechanisms could determine tic severity and the success of behavioral treatments.
Quantitative Sensory Testing in adults with Tourette syndrome.
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